AHK-Cu
AHK-Cu is a peptide composed of amino acids alanine, histidine, and lysine, with a copper ion coordinated by various parts of these three amino acids.(1) This peptide appears to be naturally present in the bloodstream and has been suggested as a potential element in regulating the growth, development, and apoptosis of vascular endothelial cells.
AHK-Cu, also known as copper AHK, has been researched for its potential in hair growth and supporting skin tissue integrity. This peptide has been suggested to exhibit its potential primarily on fibroblasts, responsible for maintaining and growing the extracellular matrix (ECM) components surrounding the cells. Fibroblasts also appear to secrete various biological substances, including the Vascular Endothelial Growth Factor (VEGF), which is suggested to promote the formation of new blood vessels.
The copper ion in AHK-Cu is suggested to be involved in enzyme activity related to collagen and elastin synthesis. These two proteins are critical components of the extracellular matrix and play a role in maintaining the skin tissues’ structural integrity. Copper ions are also suggested to exhibit antioxidant properties.
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