Pentapeptide-18 (Leuphasyl)
Pentapeptide-18 is a synthetic peptide composed of five amino acids (H-Tyr-Ala-Gly-Phe-Leu-OH) that were developed to mimic the natural process of suppressing muscle contractions, consequently reducing the development and depth of wrinkling along the epidermal barrier. Pentapeptide-18 has been hypothesized by researchers to interact with the neuroreceptors in the skin, potentially inhibiting the release of acetylcholine, a neurotransmitter that triggers muscle contractions.(1)
Pentapeptide-18 has also been suggested to impact skin cell function. It may potentially help to increase skin barrier elasticity through the stimulation of key proteins collagen and elastin. Both these proteins are considered to be a crucial component of the skin’s extracellular matrix, and their production tends to decrease over time.
Chemical Makeup(2)
Molecular Formula: C29H39N5O7
Molecular Weight: 569.65 g/mol
Other Known titles H-Tyr-Ala-Gly-Phe-Leu-OH, Leuphasyl
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